Case Study

GvHD landscape and impact analysis

Objective

To evaluate competitors and conduct impact analysis in chronic Graft versus Host Disease (cGvHD) space for a Phase-3 stem cell asset.

Approach

  • Conducted a deep dive into the cGvHD space, its treatment algorithm and various stem cell therapies in this area
  • Assessed inline and pipeline candidates for cGvHD Treatment and categorized them based on their MOA, stage of development, target patient pool, line of therapy and ROA
  • Analyzed the impact of each asset based on probability of regulatory and clinical success
  • Conducted detailed SWOT analysis of all key assets in the landscape

Outcome

  • Summarized the unmet medical needs while managing cGvHD
  • Identified potential threats for the client’s Phase 3 asset based on comprehensive competitor profiles which included details on MOA, clinical profile and potential commercial profile
  • Mapped order of entry of the key stem cell therapies

Client Benefits

  • Our analysis provided an overview of cGvHD landscape outlining the key stem cell therapies
  • Helped identify key differentiators against the competition
  • Based on the findings, the client was able to assess market dynamics and build revenue projections 
  • Our analysis and report were instrumental in the client’s strategic decision making with regards to the cGvHD market

Competitive Intelligence