Case Study

Patient journey analysis and forecast validation

Objective

Define patient opportunity and journey to validate existing Oncology Forecast.

Approach

  • Use multiple sources and investigate thoroughly to triangulate and validate assumptions
  • Study and analyze secondary literature search results, RWE, registry data and research papers to understand the flow and triangulate the findings
  • Account for patients’ journey and progression on lines of therapy help to size the opportunity and also highlight key drivers
  • Evaluate analyst reports, investor presentations, other syndicated reports to understand the business rules for sizing the later lines of treatment opportunities

Outcome

  • Sources of potential addressable patients were identified using extensive research based on our expertise in oncology
  • Built patient progression estimates using OS and PFS curves of various available therapies thus sizing the market correctly for greater impact
  • Derived insights to help evaluate impact of new product launches especially with breakthrough therapies
  • Used publicly available information to size 2L patients from 1L based on progression rate prior to the launch of novel therapies

Client Benefits

  • To have efficient and dynamic forecast models that account for all available patient opportunities
  • Have a validated addressable pool with suggestions on how to increase this pool
  • Increased precision in patient sizing by using OS-PFS progression curves. This helped create opportunities with later lines of therapy and increased sensitivity to impacts of competition

Forecasting